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論文發表

PUBLICATION

Cancer Metabolism

Su YH, Wu YZ, Ann DK, Chen JLY, Kuo CY*. Obesity promotes radioresistance through SERPINE1-mediated aggressiveness and DNA repair of triple-negative breast cancer. Cell Death Dis​. 2023 Jan 21;14(1):53.

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Wu YZ, Chen YH, Cheng CT, Ann DK, Kuo CY*. Amino acid restriction induces a long non-coding RNA UBA6-AS1 to regulate GCN2-mediated integrated stress response in breast cancer. FASEB J. 2022 Mar;36(3):e22201. 

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Cheng CT, Kuo CY, Ouyang C, Li CF, Chung Y, Chan DC, Kung HJ and Ann DK.  Metabolic Stress-Induced Phosphorylation of KAP1 Ser473 Blocks Mitochondrial Fusion in Breast Cancer Cells. Cancer Research. 2016 Sep 1;76(17):5006-18. 

Kuo CY, Cheng CT, Hou P, Lin YP, Ma H, Chung Y, Chi K, Chen Y, Li W, Kung HJ and Ann DK. HIF-1 alpha Links Mitochondrial Perturbation to the Dynamic Acquisition of Breast Cancer Tumorigenicity. Oncotarget. 2016 June 7;7(23):34052-69. 

Hou P, Kuo CY, Cheng CT, Liou JP, Ann DK and Chen Q. Intermediary Metabolite Precursor Dimethyl-2-ketoglutarate Stabilizes Hypoxia-inducible factor-1α by Inhibiting Prolyl-4-hydroxylase PHD2. PLoS One. 2014 Nov 24;9(11):e113865.

DNA damage response signaling/post-translational modification

Kuo CY, Li X, Stark JM, Shih HM and Ann DK. RNF4 Regulates DNA Double-Strand Break Repair in a Cell Cycle-Dependent Manner. Cell Cycle. 2016 Jan15(6):787-98. 

Commented in Delabaere L and Chiolo I. ReiNF4cing Repair Pathway Choice During Cell Cycle. Cell Cycle. 2016 May 15(9):1182-3. 

Kuo CY*, Li X*, Kong XQ, Luo C, Chang CC, Chung Y, Shih HM, Li KK, and Ann DK. An Arginine-rich Motif of Ring Finger Protein 4 (RNF4) Oversees the Recruitment and Degradation of the Phosphorylated and SUMOylated Krüppel-associated Box Domain-associated Protein 1 (KAP1)/TRIM28 Protein during Genotoxic Stress. J Biol Chem. 2014 Jul 25;289(30):20757-72. *equal contribution

Lee YH, Kuo CY, Stark JM, Shih HM, and Ann DK. HP1 Promotes Tumor Suppressor BRCA1 Function During the DNA Damage Response. Nucleic Acids Res. 2013 Jun;41(11):5784-98.

Review article/perspective

Wu YZ, Su YH and Kuo CY*. Stressing the Regulatory Role of Long Non-Coding RNA in the Cellular Stress Response during Cancer Progression and Therapy. Biomedicines. 2022 May 23;10(5):1212.

doi: 10.3390/biomedicines10051212.


Kuo CY* and Ann DK*. When fats commit crimes: fatty acid metabolism, cancer stemness and therapeutic resistance. Cancer Commun (Lond). 2018 Jul 11;38(1):47. doi: 10.1186/s40880-018-0317-9. (Review Article)

Cheng CT, Kuo CY and Ann DK. KAPtain in charge of multiple missions: emerging roles of KAP1. World J Biol Chem. 2014 Aug 26;5(3):308-20. doi: 10.4331/wjbc.v5.i3.308. (Review Article)

Kuo CY, Shieh C, Cai F, and Ann DK. Coordinate to Guard: Crosstalk of Phosphorylation, Sumoylation, and Ubiquitylation in DNA Damage Response. Front. Oncol. 2012 Jan 19;1:61.

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